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Emily Blunt Liza Drake Chris Evans Pete Brenner Catherine O'Hara Jackie Andy Garcia Dr. Neel Jay Duplass Larkin Brian d'Arcy James Dr. Lydell Amit Shah Eric Paley Chloe Coleman Phoebe Valerie LeBlanc Laurene Aubrey Dollar Andy Alex Klein Sidney Britt Rentschler Camille Michael Kosta Guy Schatz Nicholas Christopher McNeil Randy Bella Winkowski Luna Chapel Oaks Daughter Elle Lisic Daughter Willie Raysor Matt Selena Anduze Kate Josh Ventura Dr. Jimmy A.K. Benninghofen Dr. Bowen Chinet Scott Nicole Avis-Marie Barnes Principal Mike Stoudt Banker Lydia Castro Banker Nicole Sellars Zanna Presenter Adrian Enrique Hernandez Clinic Receptionist Rebecca Barnes Clinic Office Staffer Mandi Christine Kerr Clinic RN Joseph Mazza Neurologist Neil Kelly Jason Samantha Kacho Catherine Darryl L. Dillard Podiatrist Rowan Joseph Podiatrist Chris Marks Jeff Erica-Marie Sanchez Applicant Becca Breitfeller Applicant Andrea Laing Ellen Adrian Eppley Heather Greyson Chadwick Maria Hillary Harley Tina Devney Nixon Pain Clinic Receptionist Pat Dortch Nervous Pain Clinic Doctor Jeffrey Charles Morgan Middle Aged Doctor Jay Pearson Georgia Doctor Colby Burton Ryan Omer Mughal Agent Simonetti Cara Mantella Admissions Officer Forrest Conoly Neel's Security Guy Jamar Rivers Neel's Security Guy Dustin Lewis Mr. Jorgenson Mary Ann Hagan Patient Outside Lydell's Clinic Helen Ingebritsen Patient Outside Lydell's Clinic Alex Van Patient Outside Lydell's Clinic Quinn Bozza Undercover D.E.A. Donna DuPlantier Jane Yagoda Michael Lowry Neel's Lawyer Josefina Boneo Forbes Reporter Carolyn Jones Ellis Adrienne's Mom Elijah Forbes Emma Kowalski's Son Ryan King Sam Walter's Husband David Kronawitter Dr. Hartigan Jackie Goldston Judge Leydi Morales Loan Agent Abigail Susan Williams Lindsay - Chemo Headwrap Patient Jackson Abram Matt's Son Tristan Shufford Matt's Son Alex Mitchell Liza's Courtroom Attorney Maria Sager Neel's Housekeeper Olga Lee Rental Agent Brandon Stanley Drama Teacher Hannah Pniewski Surgical Nurse Erin Ownbey Young Jackie Kaysi J. Bradley Girl Next to Phoebe Snowden Grey Cinda Alan Wells Gambling Anonymous Doctor Cliff Lanning Crooning Doctor Valerie Boafo Extended Stay Resident Sharon Conley Judge Susan Holman Lisa Travis Group Leader Desmond Phillips Bartender Matthew Butcher Bartender Nick Arapoglou Bartender Kheri Symone Phoebe's Friend at School Kirsten Lee Anderson Clinic Mother Bliss Browne Balinese Dancer Blythe Browne Balinese Dancer Joy Browne Balinese Dancer Emily Huhtanen Balinese Dancer Savannah Johnson Balinese Dancer Jasmine Lee-Jones Balinese Dancer Ka'iulani Mcintosh-Ross Balinese Dancer Kelsey Muckle Balinese Dancer Isabel Smith Balinese Dancer Noor Tomeh Balinese Dancer Alexis Baca Pharmaceutical Model (uncredited) Tris Marie Lydell Nurse (uncredited) Shelley Jane Nervous Doctor's Crush (uncredited)