Osmosis Jones

Chris Rock Osmosis Jones (voice) Laurence Fishburne Thrax (voice) David Hyde Pierce Drix (voice) Brandy Norwood Leah (voice) Elena Franklin Shane Detorre Bill Murray Frank Detorre William Shatner Mayor Phlegmming (voice) Ron Howard Tom Colonic (voice) Kid Rock Kidney Rock (voice) Molly Shannon Mrs. Boyd Chris Elliott Bob Jonathan Adams Officer Tom (voice) Carlos Alazraqui Spanish Germ (voice) Keith Anthony Additional Character Voices (voice) Eddie Barth Conductor (voice) Sally Brooks Additional Character Voices (voice) Rodger Bumpass Joe Cramp / Announcer for Nerve News Network (voice) Michael Carven Additional Character Voices (voice) Paul Christie Dan Matter / Germ (voice) Janis Dardaris Additional Character Voices (voice) Wendy Dillon Additional Character Voices (voice) Antonio Fargas Chill the Flu Shot (voice) Eddie Frierson Frank Police Department Officer (voice) Donald Fullilove Doughnut (voice) Jackie Gonneau Additional Character Voices (voice) Shannon Gregory Additional Character Voices (voice) Richard Steven Horvitz Additional Character Voices (voice) Rif Hutton Charlie (voice) Art Kimbro Additional Character Voices (voice) Joyce Kurtz Additional Character Voices (voice) Anne Lockhart Female Red Blood Cell (voice) Sherry Lynn Trudy (voice) Danny Mann Musician Cell (voice) Mickie McGowan Brain Librarian (voice) Kenny Olson Kidney Rock Band (voice) Jason Krause Kidney Rock Band (voice) Joe C. Kidney Rock Band (voice) Stefanie Eulinberg Kidney Rock Band (voice) Jimmie Bones Kidney Rock Band (voice) Uncle Kracker Kidney Rock Band (voice) Joel Silver Police Chief (voice) (uncredited) David Ossman Scabies (voice) (uncredited) John Melendez Artie (voice) Héctor Mercado Additional Character Voices (voice) Paul Pape Male Red Blood Cell #2 (voice) Marilyn Pasekoff Additional Character Voices (voice) Chris Phillips Firefighter Doug (voice) Lynne Redding Additional Character Voices (voice) Al Rodrigo Frank Police Department Walkie Talkie (voice) Herschel Sparber Bruiser (voice) Doug Stone Police Officer Jamie (voice) Steve Susskind Mob Boss Germ (voice) Keri Tombazian Additional Character Voices (voice) Paul Tuerpe Additional Character Voices (voice) Robert Wisdom Big Germ (voice) Danny Murphy Zookeeper Superintendent Jack McCullough Zookeeper Will Dunn Oyster Boy Jackie Flynn School Janitor Kelsey Jordan Bus Girl #1 Abe Farrelly Bus Girl #2 Jesse Peter Laughing Boy John-Eliot Jordan Pea Soup Manager Nancy Byers Pea Soup Supervisor Kevin J. Flynn Docky's Clamshack Waiter Sean Gildea Dreamy Photographer Kathryn Frick Nurse #1 Nikki Tyler-Flynn Nurse #2 Elizabeth Jordan Nurse #3 Zen Gesner ER Doctor #1 Marc Hyman ER Doctor #2 Zak Penn ER Doctor #3 Diane Conrad Zoo Visitor or Staff Judith Conrad Zoo Visitor or Staff Thomas Jordan The Zoo Visitor or Staff Sydney J. Bartholomew Jr. Zoo Visitor or Staff Erica Johnson Zoo Visitor or Staff Bo Cleary Pea Soup Staff Bruce McIntyre Pea Soup Staff Colleen O'Donnell Docky's Clamshack Docky The Bikini Gang Joe Murphy The Bikini Gang Brian Mone Police Officer Sean Fitzgerald Police Officer Grace Costa ER Nurse Emily O’Donnell School Girl